Genetic Testing
Researchers at the University of Pennsylvania has agreed to assist with
investigation of a possible genetic test for Juvenile Cardiomyopathy
(JCM) in Toy Manchester Terriers. In order to proceed, however,
DNA samples from at least 10 affected puppies must be collected via
necropsy. Because samples were not gathered in all previous
autopsies, we currently only have a few samples on file.
Please check the Postmortem Examination
section of this website for information on necropsies, necropsy support
and protocols for collecting and submitting DNA information (see Gross
Pathology Protocol). It is imperative that puppies who die
suddenly be necropsied and that samples indicated be taken and
submitted.
An investigation of the genetic basis of cardiomyopathy in the Toy
Manchester was completed in 2010. Read the completed paper
here.