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Juvenile Dilated Cardiomyopathy in Toy Manchesters

The Canadian and American Manchester Terrier Clubs are pleased to announce that the genetic mutation causing Juvenile Dilated Cardiomyopathy (JDCM) in Toy Manchester Terriers has been identified. A test is now available from the University of Minnesota's Canine Genetics Lab. This test will allow breeders to determine the genetic status (clear, carrier or affected) of their dogs and puppies.

The CMTC and AMTC wish to thank the many owners and breeders around the world whose support and participation led to the investigation of JDCM and, ultimately, development of a test that will allow breeders to make informed choices. Sincere thanks are also extended to the researchers who made this discovery possible, including Dr. Eva Furrow and the genetics team at the University of Minnesota's College of Veterinary Medicine; Dr. Paula Henthorn and Dr. Meg Sleeper at the University of Pennsylvannia's School of Veterinary Medicine; and Dr. Etienne Coté, Dr. Shannon Martinson and their colleagues at the University of Prince Edward Island's Atlantic Veterinary College. Their willingness to tackle a poorly understood problem in a very small breed with limited available funds is a testament to their commitment to animal welfare and scientific inquiry.

We encourage Toy Manchester Terrier owners and breeders to explore these pages to learn more about the disease, testing and recommendations for safeguarding genetic health of the breed when applying this new tool in your breeding program.


  • JDCM Test Announcement (PDF)
  • What is Juvenile Cardiomyopathy?​
  • Testing
    • University of Minnesota Genetics Lab 
    • Frequently Asked Questions 
    • Information for Breeders
  • Completed JCM Research
  • Study Contacts 

News!

  • Check out our Completed Research page for results of Standard Manchester sampling and updated statistics on JCM testing as of November 2016.
  • The CMTC and AMTC thank Nicole Tate from the University of Minnesota for her September 2016 presentation on Juvenile Cardioymopathy and Xanthinuria at the American Manchester Terrier Club National Specialty.  Click the links below to view the presentation slides and hear recorded audio of her presentation.
    • Presentation Slides (PDF)
    • Audio of Presentation (.WAV) [begins on slide 5]
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