Xanthinuria in Manchester Terriers
In August 2015, Dr. Eva Furrow, VMD, PhD, Dip ACVIM, Assistant Professor of Small Animal Medicine at University of Minnesota, College of Veterinary Medicine and her team concluded a very short but successful investigation of hereditary xanthinuria in Toy Manchester Terriers. Xanthinuria simply means an excess of xanthine (a by-product of the metabolismof some proterins) in the urine. In affected dogs, xanthine may accumulate in blood and urine and can cause urinary stones (bladder and/or kidney) and kidney failure.
As a result of her research, Dr. Furrow has identified a DNA test to detect carriers of the autosomal recessive gene causing this disorder. The Canadian Manchester Terrier Club is now funding a sampling of 25 Standard Manchester Terriers to determine (to the extent possible) the presence of the gene in that population.
We encourage all Manchester Terrier and English Toy Terrier owners and breeders to explore these pages and learn more about what we have learned, our current research activities and how you can help research efforts.
As a result of her research, Dr. Furrow has identified a DNA test to detect carriers of the autosomal recessive gene causing this disorder. The Canadian Manchester Terrier Club is now funding a sampling of 25 Standard Manchester Terriers to determine (to the extent possible) the presence of the gene in that population.
We encourage all Manchester Terrier and English Toy Terrier owners and breeders to explore these pages and learn more about what we have learned, our current research activities and how you can help research efforts.
